Top 15 Angel Investors in Chicago (2026)
Chicago is home to 1,219 angel investors and VCs in the AngelBacked database. The most active — ranked below by number of disclosed portfolio investments — include Lilian Chen, Tyler Mayoras and Rachel Geller. Their portfolios concentrate in Health Care, E-commerce and Wellness.
- 1View profileLilian ChenVP of Operations at PartySlate97 portfolio investments
Notable investments: Agenteur, Porter Road Butcher, Moova, Leap
Health CareE-commercePayments - 2View profileTyler MayorasManaging Director, Food & Beverage at Manna Tree96 portfolio investments
Notable investments: Hortau, Danimer Scientific, PayIt, Glori Energy
AdvertisingHealth CareTelecommunications - 3View profileRachel GellerManaging Director at Insight Partners96 portfolio investments
Notable investments: CRED, Pollinate Networks, Restream, Pathlight
Data IntegrationAsset ManagementE-commerce - 4View profileSanjiv ShahManaging Director at N/A96 portfolio investments
Notable investments: National Cardiovascular Partners, Advance Health, Eaton, Genstar Capital
Health CareHospitalsEmail - 5View profileChris GirgentiManaging Partner at Pritzker Group86 portfolio investments
Notable investments: Wise Apple, Flyhomes, Wander Beauty, Apervita
Health CareDelivery ServiceNavigation - 6View profileJason MehringManaging Director at N/A84 portfolio investments
Notable investments: Acorns, Goldfinch Biopharma, Domo, Icelandic Glacial
Health CareTelecommunicationsE-commerce - 7View profileRob CollinsManaging Partner, North American Infrastructure at 3i Group plc84 portfolio investments
Notable investments: Everis Group, Carbonite, Futaste, DiBcom
Health CareWearablesE-commerce - 8View profileSonia NagarBoard Member at SNAK Venture Partners83 portfolio investments
Notable investments: Wise Apple, Flyhomes, Wander Beauty, Apervita
Health CareE-commerceDatabases - 9View profileKeith FreemanManaging Director at N/A82 portfolio investments
Notable investments: Hortau, Danimer Scientific, PayIt, Glori Energy
Health CareTelecommunicationsTransportation - 10View profileMaurice DoyleManaging Director at N/A82 portfolio investments
Notable investments: Hortau, Danimer Scientific, PayIt, Glori Energy
Health CareTelecommunicationsTransportation - 11View profileTom GroosPartner at Heartland Automation LLC81 portfolio investments
Notable investments: CommSafe AI, Elroy Air, LicenseStream, Rune Labs
DiningHealth CareWearables - 12View profileConnor RyanPartner at Bridge Venture Fund80 portfolio investments
Notable investments: KSQ Therapeutics, Noema Pharma, Quartet Health, Notarize
Health CareE-commerceMedical Testing - 13View profileGreg BarnesPartner at Hyde Park Venture Partners78 portfolio investments
Notable investments: TurboAppeal, Bridgit, Terminus, Ahalogy
Health CareHospitalsE-commerce - 14View profileLauren BugayManaging Director at N/A78 portfolio investments
Notable investments: Figure, EKuaibao, Eaze, Kespry
AdvertisingWearablesE-Learning - 15View profileWilliam ConnellVice President and Controller at N/A78 portfolio investments
Notable investments: Figure, EKuaibao, Eaze, Kespry
AdvertisingWearablesE-Learning
Methodology
Investors are ranked by the number of disclosed portfolio investments recorded in the AngelBacked database of Chicago-based angels, VCs, and family offices. Rankings refresh as new investments are disclosed. Portfolio counts reflect publicly known deals and may understate an investor's full activity.
Frequently Asked Questions
Who is the most active angel investor in Chicago?
Based on disclosed portfolio investments, Lilian Chen (PartySlate) is the most active angel investor in Chicago in our database, with 97 portfolio investments.
How many angel investors are in Chicago?
AngelBacked's database includes 1,219 angel investors and VCs based in Chicago. This page ranks the 15 most active by portfolio size.
What sectors do Chicago angel investors fund?
The most common sectors among Chicago's top angel investors are Health Care, E-commerce, Wellness, Women Founded and Transportation.
How do I contact angel investors in Chicago?
Each investor profile on AngelBacked includes verified contact details, portfolio companies, and sector focus. Warm introductions convert best, but a concise cold email referencing a relevant portfolio company also works — mention why your startup fits their investment pattern.
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