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    AngelBacked
    San DiegoUpdated July 2026

    Top 15 Angel Investors in San Diego (2026)

    San Diego is home to 305 angel investors and VCs in the AngelBacked database. The most active — ranked below by number of disclosed portfolio investments — include Christopher Herr, Tracy Maziek and David Hickman. Their portfolios concentrate in Health Care, Biotech and Healthcare.

    1. 1
      Christopher HerrSenior Managing Director at N/A
      92 portfolio investments

      Notable investments: Bi02 Medical, Epic Healthcare Staffing, Cardiac Dimensions, Syros Pharmaceuticals

      Health CareHospitalsEyewear
    2. 2
      Tracy MaziekManaging Director at N/A
      92 portfolio investments

      Notable investments: Bi02 Medical, Epic Healthcare Staffing, Cardiac Dimensions, Syros Pharmaceuticals

      Health CareHospitalsEyewear
    3. 3
      David HickmanManaging Director at N/A
      92 portfolio investments

      Notable investments: Bi02 Medical, Epic Healthcare Staffing, Cardiac Dimensions, Syros Pharmaceuticals

      Health CareHospitalsEyewear
    4. 4
      Killu SanbornManaging Director at N/A
      92 portfolio investments

      Notable investments: Bi02 Medical, Epic Healthcare Staffing, Cardiac Dimensions, Syros Pharmaceuticals

      Health CareHospitalsEyewear
    5. 5
      Manav BhanotSoftware Development Engineer II at Amazon
      86 portfolio investments

      Notable investments: Vouch Financial, Chai, Notion, iPourIt

      Health CareE-commerceHome Automation
    6. 6
      Lucian IancoviciPartner and Managing Director, TPG Life Science Innovations at N/A
      81 portfolio investments

      Notable investments: PharmEasy, Gro Intelligence, Avanan, Albireo

      AdvertisingDiningHealth Care
    7. 7
      Yan LiuSenior Staff Engineer, Manager at N/A
      79 portfolio investments

      Notable investments: Shadowfax, MoveInSync, Dunamu, Bell.ai

      Health CareBluetoothTraining
    8. 8
      Swapna GuntakaSenior Staff Programmer Analyst at N/A
      79 portfolio investments

      Notable investments: Shadowfax, MoveInSync, Dunamu, Bell.ai

      Health CareBluetoothTraining
    9. 9
      Richard TapalagaDirector at N/A
      79 portfolio investments

      Notable investments: Shadowfax, MoveInSync, Dunamu, Bell.ai

      Health CareTrainingWearables
    10. 10
      Anna H. ChenBoard Member at N/A
      72 portfolio investments

      Notable investments: Zeltiq Aesthetics, BARRX Medical, The CORE Institute, Lassen Therapeutics

      Health CareWellnessHealthcare Services
    11. 11
      John BonhardVice President at N/A
      72 portfolio investments

      Notable investments: InSkin Media, Thread, Monica Vinader, SMARTASSISTANT

      AdvertisingE-commerceWomen Founded
    12. 12
      Perry NisenIndependent Director, Chair of Science and Technology at N/A
      67 portfolio investments

      Notable investments: ENYO Pharma, Y-mAbs Therapeutics, NuCana, Histogenics

      Health CareGeneticsWomen Founded
    13. 13
      Paul GraysonPartner at N/A
      62 portfolio investments

      Notable investments: Black Diamond Therapeutics, Kyras Therapeutics, CRISPR Therapeutics, Aligos Therapeutics

      Health CareGeneticsWomen Founded
    14. 14
      Kevin KinsellaFounding Partner Emeritus at N/A
      61 portfolio investments

      Notable investments: Talla, NanoNets, Node, Enlibrium

      AdvertisingHealth CareData Integration
    15. 15
      Dominik NaczynskiManaging Director at N/A
      50 portfolio investments

      Notable investments: Black Diamond Therapeutics, AveXis, Aligos Therapeutics, Tyra Biosciences

      Health CareWomen FoundedWomen Led

    Methodology

    Investors are ranked by the number of disclosed portfolio investments recorded in the AngelBacked database of San Diego-based angels, VCs, and family offices. Rankings refresh as new investments are disclosed. Portfolio counts reflect publicly known deals and may understate an investor's full activity.

    Frequently Asked Questions

    Who is the most active angel investor in San Diego?

    Based on disclosed portfolio investments, Christopher Herr (N/A) is the most active angel investor in San Diego in our database, with 92 portfolio investments.

    How many angel investors are in San Diego?

    AngelBacked's database includes 305 angel investors and VCs based in San Diego. This page ranks the 15 most active by portfolio size.

    What sectors do San Diego angel investors fund?

    The most common sectors among San Diego's top angel investors are Health Care, Biotech, Healthcare, Biotechnology and Women Founded.

    How do I contact angel investors in San Diego?

    Each investor profile on AngelBacked includes verified contact details, portfolio companies, and sector focus. Warm introductions convert best, but a concise cold email referencing a relevant portfolio company also works — mention why your startup fits their investment pattern.

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    Browse All 305 San Diego Investors

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